Proteins in the kinetochore generate forces to drive chromosomes movement

To accomplish the precise segregation of chromosomes, kinetochore must be form incentive interaction with motor proteins. Any error happens in chromosome led to aneuploidy that consider as main factor cause cancers and many birth defects. Kinetochore is a proteinous complex structure consist hundred It’s performed functions such it connects movement chromosomes microtubule, acts observer for biorentation, beside role segregation. In this review we described proteins content important these generating forces drive also clarified some experiments used identify support their functions.